Development and validation of an LC-MS/MS method for determination of hydroxychloroquine, its two metabolites, and azithromycin in EDTA-treated human plasma

BACKGROUND: Hydroxychloroquine (HCQ) and azithromycin (AZM) are antimalarial drugs recently reported to be active against severe acute respiratory syndrome coronavirus- 2 (SARS-CoV-2), which is causing the global COVID-19 pandemic. In an emergency response to the pandemic, we aimed to develop a quan...

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Detalles Bibliográficos
Autores principales: Sok, Vong, Marzan, Florence, Gingrich, David, Aweeka, Francesca, Huang, Liusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935301/
https://www.ncbi.nlm.nih.gov/pubmed/33667247
http://dx.doi.org/10.1371/journal.pone.0247356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935301/
https://www.ncbi.nlm.nih.gov/pubmed/33667247
http://dx.doi.org/10.1371/journal.pone.0247356

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