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Single-cell transcriptomic analysis of mIHC images via antigen mapping
Highly multiplexed immunohistochemistry (mIHC) enables the staining and quantification of dozens of antigens in a tissue section with single-cell resolution. However, annotating cell populations that differ little in the profiled antigens or for which the antibody panel does not include specific mar...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935366/ https://www.ncbi.nlm.nih.gov/pubmed/33674303 http://dx.doi.org/10.1126/sciadv.abc5464 |