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Single-cell transcriptomic analysis of mIHC images via antigen mapping

Highly multiplexed immunohistochemistry (mIHC) enables the staining and quantification of dozens of antigens in a tissue section with single-cell resolution. However, annotating cell populations that differ little in the profiled antigens or for which the antibody panel does not include specific mar...

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Detalles Bibliográficos
Autores principales: Govek, Kiya W., Troisi, Emma C., Miao, Zhen, Aubin, Rachael G., Woodhouse, Steven, Camara, Pablo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935366/
https://www.ncbi.nlm.nih.gov/pubmed/33674303
http://dx.doi.org/10.1126/sciadv.abc5464