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Evaluation of Sustained Virologic Response as a Relevant Surrogate Endpoint for Long-term Outcomes of Hepatitis C Virus Infection

BACKGROUND: The causal link of sustained virologic response (SVR) with outcome has been challenged. With improved SVR rates with direct-acting antivirals (DAAs), the benefit of SVR would be expected to diminish if the association with outcome is not causal. METHODS: Data were collected for patients...

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Detalles Bibliográficos
Autores principales: Krassenburg, Lisette A P, Zanjir, Wayel R, Georgie, Firas, Stotland, Emily, Janssen, Harry L A, Hansen, Bettina E, Feld, Jordan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935378/
https://www.ncbi.nlm.nih.gov/pubmed/32052014
http://dx.doi.org/10.1093/cid/ciaa144