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Whole-Exome Sequencing in Patients Affected by Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Reveals New Variants Potentially Contributing to the Phenotype

BACKGROUND: Adverse drug reactions (ADRs) are frequent occurring events that can essentially be defined as harmful or unpleasant symptoms secondary to the use of a medicinal product. ADRs involve a wide spectrum of clinical manifestations ranging from minor itching and rash to life-threatening react...

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Detalles Bibliográficos
Autores principales: Fonseca, Dora Janeth, Morel, Adrien, Llinás-Caballero, Kevin, Bolívar-Salazar, David, Laissue, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935440/
https://www.ncbi.nlm.nih.gov/pubmed/33688237
http://dx.doi.org/10.2147/PGPM.S289869