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Rat dorsal horn neurons primed by stress develop a long-lasting manifest sensitization after a short-lasting nociceptive low back input

BACKGROUND: A single injection of nerve growth factor (NGF) into a low back muscle induces a latent sensitization of rat dorsal horn neurons (DHNs) that primes for a manifest sensitization by a subsequent second NGF injection. Repeated restraint stress also causes a latent DHN sensitization. OBJECTI...

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Detalles Bibliográficos
Autores principales: Singaravelu, Sathish Kumar, Hoheisel, Ulrich, Mense, Siegfried, Treede, Rolf-Detlef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935483/
https://www.ncbi.nlm.nih.gov/pubmed/33688602
http://dx.doi.org/10.1097/PR9.0000000000000904