Retrograde ERK activation waves drive base-to-apex multicellular flow in murine cochlear duct morphogenesis

A notable example of spiral architecture in organs is the mammalian cochlear duct, where the morphology is critical for hearing function. Genetic studies have revealed necessary signaling molecules, but it remains unclear how cellular dynamics generate elongating, bending, and coiling of the cochlea...

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Detalles Bibliográficos
Autores principales: Ishii, Mamoru, Tateya, Tomoko, Matsuda, Michiyuki, Hirashima, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935486/
https://www.ncbi.nlm.nih.gov/pubmed/33667159
http://dx.doi.org/10.7554/eLife.61092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935486/
https://www.ncbi.nlm.nih.gov/pubmed/33667159
http://dx.doi.org/10.7554/eLife.61092

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