Brain endothelial cell TRPA1 channels initiate neurovascular coupling

Cerebral blood flow is dynamically regulated by neurovascular coupling to meet the dynamic metabolic demands of the brain. We hypothesized that TRPA1 channels in capillary endothelial cells are stimulated by neuronal activity and instigate a propagating retrograde signal that dilates upstream parenc...

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Detalles Bibliográficos
Autores principales: Thakore, Pratish, Alvarado, Michael G, Ali, Sher, Mughal, Amreen, Pires, Paulo W, Yamasaki, Evan, Pritchard, Harry AT, Isakson, Brant E, Tran, Cam Ha T, Earley, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935492/
https://www.ncbi.nlm.nih.gov/pubmed/33635784
http://dx.doi.org/10.7554/eLife.63040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935492/
https://www.ncbi.nlm.nih.gov/pubmed/33635784
http://dx.doi.org/10.7554/eLife.63040

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