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A Sensitive Plasma Insulin Immunoassay to Establish the Diagnosis of Congenital Hyperinsulinism

BACKGROUND: The diagnosis of congenital hyperinsulinism (CHI) may be hampered by a plasma (p-) insulin detection limit of 12–18 pmol/L (2–3 mU/L). OBJECTIVE: To evaluate the diagnostic performance of a sensitive insulin immunoassay and to find the optimal p-insulin cut-off for the diagnosis of CHI....

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Detalles Bibliográficos
Autores principales: Siersbæk, Julie, Larsen, Annette Rønholt, Nybo, Mads, Christesen, Henrik Thybo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935514/
https://www.ncbi.nlm.nih.gov/pubmed/33679602
http://dx.doi.org/10.3389/fendo.2020.614993