Cargando…

High-throughput fetal fraction amplification increases analytical performance of noninvasive prenatal screening

PURPOSE: The percentage of a maternal cell-free DNA (cfDNA) sample that is fetal-derived (the fetal fraction; FF) is a key driver of the sensitivity and specificity of noninvasive prenatal screening (NIPS). On certain NIPS platforms, >20% of women with high body mass index (and >5% overall) re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Welker, Noah C., Lee, Albert K., Kjolby, Rachel A. S., Wan, Helen Y., Theilmann, Mark R., Jeon, Diana, Goldberg, James D., Haas, Kevin R., Muzzey, Dale, Chu, Clement S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935715/ https://www.ncbi.nlm.nih.gov/pubmed/33190143 http://dx.doi.org/10.1038/s41436-020-01009-5

Ejemplares similares

Response to “Noninvasive prenatal screening at low fetal fraction: comparing whole‐genome sequencing and single‐nucleotide polymorphism methods”
por: Muzzey, Dale, et al.
Publicado: (2017)

The impact of HBB‐related hemoglobinopathies carrier status on fetal fraction in noninvasive prenatal screening
por: Putra, Manesha, et al.
Publicado: (2022)

Noninvasive prenatal screening for patients with high body mass index: Evaluating the impact of a customized whole genome sequencing workflow on sensitivity and residual risk
por: Muzzey, Dale, et al.
Publicado: (2019)

Bioinformatics Approaches for Fetal DNA Fraction Estimation in Noninvasive Prenatal Testing
por: Peng, Xianlu Laura, et al.
Publicado: (2017)

Factors Affecting the Fetal Fraction in Noninvasive Prenatal Screening: A Review
por: Deng, Cechuan, et al.
Publicado: (2022)

Noninvasive Prenatal Measurement of the Fetal Genome
por: Fan, H. Christina, et al.
Publicado: (2012)

Technology-Driven Noninvasive Prenatal Screening Results Disclosure and Management
por: Arjunan, Aishwarya, et al.
Publicado: (2020)

Inferring fetal fractions from read heterozygosity empowers the noninvasive prenatal screening
por: Dang, Minghao, et al.
Publicado: (2019)

Calculating the fetal fraction for noninvasive prenatal testing based on genome‐wide nucleosome profiles
por: Straver, Roy, et al.
Publicado: (2016)

Correction: Inferring fetal fractions from read heterozygosity empowers the noninvasive prenatal screening
por: Dang, Minghao, et al.
Publicado: (2019)

Hemolysis and Fetal Fraction in Cell-Free DNA Blood Collection Tubes for Noninvasive Prenatal Testing
por: Stokowski, Renee, et al.
Publicado: (2020)

A multivariate modeling method for the prediction of low fetal fraction before noninvasive prenatal testing
por: Hu, Liang, et al.
Publicado: (2021)

Combined fetal fraction to analyze the Z-score accuracy of noninvasive prenatal testing for fetal trisomies 13, 18, and 21
por: Yang, Jiexia, et al.
Publicado: (2023)

Clinical experience across the fetal‐fraction spectrum of a non‐invasive prenatal screening approach with low test‐failure rate
por: Hancock, S., et al.
Publicado: (2020)

Combining the use of a fetal fraction‐based risk algorithm and probability of an informative redraw in noninvasive prenatal testing for fetal aneuploidy
por: Benn, Peter, et al.
Publicado: (2019)

White blood cell count affects fetal fraction and test failure rates in noninvasive prenatal screening
por: Qiao, Longwei, et al.
Publicado: (2023)

Strategies to minimize false positives and interpret novel microdeletions based on maternal copy-number variants in 87,000 noninvasive prenatal screens
por: Kaseniit, Kristjan Eerik, et al.
Publicado: (2018)

Maternal and fetal factors influencing fetal fraction: A retrospective analysis of 153,306 pregnant women undergoing noninvasive prenatal screening
por: Deng, Cechuan, et al.
Publicado: (2023)

Cell‐free DNA fetal fraction in twin gestations in single‐nucleotide polymorphism‐based noninvasive prenatal screening
por: Hedriana, Herman, et al.
Publicado: (2019)

Evaluation of a Microhaplotype-Based Noninvasive Prenatal Test in Twin Gestations: Determination of Paternity, Zygosity, and Fetal Fraction
por: Bai, Zhaochen, et al.
Publicado: (2020)

Fetal Sex Results of Noninvasive Prenatal Testing and Differences With Ultrasonography
por: Dhamankar, Rupin, et al.
Publicado: (2020)

Noninvasive Fetal Trisomy (NIFTY) test: an advanced noninvasive prenatal diagnosis methodology for fetal autosomal and sex chromosomal aneuploidies
por: Jiang, Fuman, et al.
Publicado: (2012)

Comment on “Noninvasive prenatal screening at low fetal fraction: comparing whole‐genome sequencing and single‐nucleotide polymorphism methods”
por: Ryan, Allison, et al.
Publicado: (2017)

Evidence for feasibility of fetal trophoblastic cell‐based noninvasive prenatal testing
por: Breman, Amy M., et al.
Publicado: (2016)

Noninvasive prenatal testing detects microdeletion abnormalities of fetal chromosome 15
por: Yin, Lianli, et al.
Publicado: (2019)

Clinical application of noninvasive prenatal testing in the detection of fetal chromosomal diseases
por: Pang, Yu, et al.
Publicado: (2021)

Noninvasive prenatal diagnosis targeting fetal nucleated red blood cells
por: Chen, Yanyu, et al.
Publicado: (2022)

Early noninvasive prenatal paternity testing by targeted fetal DNA analysis
por: Damour, Géraldine, et al.
Publicado: (2023)

Calculation of Fetal Fraction for Non-Invasive Prenatal Testing
por: Cserhati, Matthew
Publicado: (2021)

Noninvasive Prenatal Diagnosis of Fetal RHD Status Using Cell-free Fetal DNA in Maternal Plasma
por: Ahmadi, Mohammad Hossein, et al.
Publicado: (2022)

Efficiency of noninvasive prenatal testing for the detection of fetal microdeletions and microduplications in autosomal chromosomes
por: Pei, Yuanyuan, et al.
Publicado: (2020)

Noninvasive prenatal prediction of fetal haplotype with Spearman rank correlation analysis model
por: Hanxiao, Du, et al.
Publicado: (2022)

Correction: Noninvasive prenatal diagnosis targeting fetal nucleated red blood cells
por: Chen, Yanyu, et al.
Publicado: (2023)

Noninvasive prenatal screening for fetal common sex chromosome aneuploidies from maternal blood
por: Zhang, Bin, et al.
Publicado: (2017)

Amniocentesis and Next Generation Sequencing (NGS)-Based Noninvasive Prenatal DNA Testing (NIPT) for Prenatal Diagnosis of Fetal Chromosomal Disorders
por: Qi, Qi-Ge, et al.
Publicado: (2021)

Noninvasive Prenatal Diagnosis of Fetal Trisomy 18 and Trisomy 13 by Maternal Plasma DNA Sequencing
por: Chen, Eric Z., et al.
Publicado: (2011)

An efficient method for noninvasive prenatal diagnosis of fetal trisomy 13, trisomy 18, and trisomy 21
por: Sun, Xiaohan, et al.
Publicado: (2019)

Clinical value for the detection of fetal chromosomal deletions/duplications by noninvasive prenatal testing in clinical practice
por: Gou, Lingshan, et al.
Publicado: (2021)

Noninvasive fetal genotyping of single nucleotide variants and linkage analysis for prenatal diagnosis of monogenic disorders
por: Wu, Wenman, et al.
Publicado: (2022)

Early noninvasive prenatal detection of a fetal CRB1 mutation causing Leber congenital amaurosis
por: Bustamante-Aragones, Ana, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_s8ekhiudvpcm7a0v33rt1u1n84