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α‐Emitting cancer therapy using (211)At‐AAMT targeting LAT1
α‐Methyl‐l‐tyrosine (AMT) has a high affinity for the cancer‐specific l‐type amino acid transporter 1 (LAT1). Therefore, we established an anti‐cancer therapy, with (211)At‐labeled α‐methyl‐l‐tyrosine ((211)At‐AAMT) as a carrier of (211)At into tumors. (211)At‐AAMT had high affinity for LAT1, inhibi...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935802/ https://www.ncbi.nlm.nih.gov/pubmed/33277750 http://dx.doi.org/10.1111/cas.14761 |