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Short‐term cultured autologous peripheral blood mononuclear cells as a potential immunogen to activate Tax‐specific CTL response in adult T‐cell leukemia patients

Activation of CD8(+) Tax‐specific CTL is a new therapeutic concept for adult T‐cell leukemia (ATL) caused by HTLV‐1. A recent clinical study of the dendritic cell vaccine pulsed with Tax peptides corresponding to CTL epitopes showed promising outcomes in ATL patients possessing limited human leukocy...

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Detalles Bibliográficos
Autores principales: Ishizawa, Miku, Ganbaatar, Undrakh, Hasegawa, Atsuhiko, Takatsuka, Natsuko, Kondo, Nobuyo, Yoneda, Takeru, Katagiri, Kuniko, Masuda, Takao, Utsunomiya, Atae, Kannagi, Mari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935807/
https://www.ncbi.nlm.nih.gov/pubmed/33410215
http://dx.doi.org/10.1111/cas.14800