Optimal sampling strategies for darunavir and external validation of the underlying population pharmacokinetic model

PURPOSE: A variety of diagnostic methods are available to validate the performance of population pharmacokinetic models. Internal validation, which applies these methods to the model building dataset and to additional data generated through Monte Carlo simulations, is often sufficient, but external...

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Detalles Bibliográficos
Autores principales: Stillemans, Gabriel, Belkhir, Leila, Vandercam, Bernard, Vincent, Anne, Haufroid, Vincent, Elens, Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Pharmacokinetics and Disposition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935830/
https://www.ncbi.nlm.nih.gov/pubmed/33175180
http://dx.doi.org/10.1007/s00228-020-03036-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935830/
https://www.ncbi.nlm.nih.gov/pubmed/33175180
http://dx.doi.org/10.1007/s00228-020-03036-2

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