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Structural basis for promiscuous action of monoterpenes on TRP channels

Monoterpenes are major constituents of plant-derived essential oils and have long been widely used for therapeutic and cosmetic applications. The monoterpenes menthol and camphor are agonists or antagonists for several TRP channels such as TRPM8, TRPV1, TRPV3 and TRPA1. However, which regions within...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi Hong Dung, Itoh, Satoru G., Okumura, Hisashi, Tominaga, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935860/
https://www.ncbi.nlm.nih.gov/pubmed/33674682
http://dx.doi.org/10.1038/s42003-021-01776-0