Prevalence of germline pathogenic variants in 22 cancer susceptibility genes in Swedish pediatric cancer patients

Up to 10% of pediatric cancer patients harbor pathogenic germline variants in one or more cancer susceptibility genes. A recent study from the US reported pathogenic variants in 22 out of 60 analyzed autosomal dominant cancer susceptibility genes, implicating 8.5% of pediatric cancer patients. Here...

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Detalles Bibliográficos
Autores principales: von Stedingk, Kristoffer, Stjernfelt, Karl-Johan, Kvist, Anders, Wahlström, Cecilia, Kristoffersson, Ulf, Stenmark-Askmalm, Marie, Wiebe, Thomas, Hjorth, Lars, Koster, Jan, Olsson, Håkan, Øra, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935871/
https://www.ncbi.nlm.nih.gov/pubmed/33674644
http://dx.doi.org/10.1038/s41598-021-84502-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935871/
https://www.ncbi.nlm.nih.gov/pubmed/33674644
http://dx.doi.org/10.1038/s41598-021-84502-4

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