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IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection

SARS-CoV-2 virus has infected more than 92 million people worldwide resulting in the Coronavirus disease 2019 (COVID-19). Using a rhesus macaque model of SARS-CoV-2 infection, we have characterized the transcriptional signatures induced in the lungs of juvenile and old macaques following infection....

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Detalles Bibliográficos
Autores principales: Rosa, Bruce A., Ahmed, Mushtaq, Singh, Dhiraj K., Choreño-Parra, José Alberto, Cole, Journey, Jiménez-Álvarez, Luis Armando, Rodríguez-Reyna, Tatiana Sofía, Singh, Bindu, Gonzalez, Olga, Carrion, Ricardo, Schlesinger, Larry S., Martin, John, Zúñiga, Joaquín, Mitreva, Makedonka, Kaushal, Deepak, Khader, Shabaana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935909/
https://www.ncbi.nlm.nih.gov/pubmed/33674719
http://dx.doi.org/10.1038/s42003-021-01829-4