RNA-seq and GSEA identifies suppression of ligand-gated chloride efflux channels as the major gene pathway contributing to form deprivation myopia

Currently there is no consensus regarding the aetiology of the excessive ocular volume that characterizes high myopia. Thus, we aimed to test whether the gene pathways identified by gene set enrichment analysis of RNA-seq transcriptomics refutes the predictions of the Retinal Ion Driven Efflux (RIDE...

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Detalles Bibliográficos
Autores principales: Vocale, Loretta Giummarra, Crewther, Sheila, Riddell, Nina, Hall, Nathan E., Murphy, Melanie, Crewther, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935918/
https://www.ncbi.nlm.nih.gov/pubmed/33674625
http://dx.doi.org/10.1038/s41598-021-84338-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935918/
https://www.ncbi.nlm.nih.gov/pubmed/33674625
http://dx.doi.org/10.1038/s41598-021-84338-y

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