Expanding the drug discovery space with predicted metabolite–target interactions

Metabolites produced in the human gut are known modulators of host immunity. However, large-scale identification of metabolite–host receptor interactions remains a daunting challenge. Here, we employed computational approaches to identify 983 potential metabolite–target interactions using the Inflam...

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Detalles Bibliográficos
Autores principales: Nuzzo, Andrea, Saha, Somdutta, Berg, Ellen, Jayawickreme, Channa, Tocker, Joel, Brown, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935942/
https://www.ncbi.nlm.nih.gov/pubmed/33674782
http://dx.doi.org/10.1038/s42003-021-01822-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935942/
https://www.ncbi.nlm.nih.gov/pubmed/33674782
http://dx.doi.org/10.1038/s42003-021-01822-x

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