Insights on autophagosome–lysosome tethering from structural and biochemical characterization of human autophagy factor EPG5

Pivotal to the maintenance of cellular homeostasis, macroautophagy (hereafter autophagy) is an evolutionarily conserved degradation system that involves sequestration of cytoplasmic material into the double-membrane autophagosome and targeting of this transport vesicle to the lysosome/late endosome...

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Detalles Bibliográficos
Autores principales: Nam, Sung-Eun, Cheung, Yiu Wing Sunny, Nguyen, Thanh Ngoc, Gong, Michael, Chan, Samuel, Lazarou, Michael, Yip, Calvin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935953/
https://www.ncbi.nlm.nih.gov/pubmed/33674710
http://dx.doi.org/10.1038/s42003-021-01830-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935953/
https://www.ncbi.nlm.nih.gov/pubmed/33674710
http://dx.doi.org/10.1038/s42003-021-01830-x

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