RNF8 ubiquitinates RecQL4 and promotes its dissociation from DNA double strand breaks

Ubiquitination-dependent DNA damage response (DDR) signals play a critical role in the cellular choice of DNA damage repair pathways. Human DNA helicase RecQL4 participates in DNA replication and repair, and loss of RecQL4 is associated with autosomal recessive genetic disorders characterized by gen...

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Detalles Bibliográficos
Autores principales: Tan, Qunsong, Niu, Kaifeng, Zhu, Yuqi, Chen, Zixiang, Li, Yueyang, Li, Mengge, Wei, Di, Balajee, Adayabalam S., Fang, Hongbo, Zhao, Yongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935965/
https://www.ncbi.nlm.nih.gov/pubmed/33674555
http://dx.doi.org/10.1038/s41389-021-00315-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935965/
https://www.ncbi.nlm.nih.gov/pubmed/33674555
http://dx.doi.org/10.1038/s41389-021-00315-0

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