Cargando…

RNF8 ubiquitinates RecQL4 and promotes its dissociation from DNA double strand breaks

Ubiquitination-dependent DNA damage response (DDR) signals play a critical role in the cellular choice of DNA damage repair pathways. Human DNA helicase RecQL4 participates in DNA replication and repair, and loss of RecQL4 is associated with autosomal recessive genetic disorders characterized by gen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tan, Qunsong, Niu, Kaifeng, Zhu, Yuqi, Chen, Zixiang, Li, Yueyang, Li, Mengge, Wei, Di, Balajee, Adayabalam S., Fang, Hongbo, Zhao, Yongliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935965/ https://www.ncbi.nlm.nih.gov/pubmed/33674555 http://dx.doi.org/10.1038/s41389-021-00315-0

Ejemplares similares

RecQL4-Aurora B kinase axis is essential for cellular proliferation, cell cycle progression, and mitotic integrity
por: Fang, Hongbo, et al.
Publicado: (2018)

RecQL4 Helicase Amplification Is Involved in Human Breast Tumorigenesis
por: Fang, Hongbo, et al.
Publicado: (2013)

Identification of RecQL1 as a Holliday junction processing enzyme in human cell lines
por: LeRoy, Gary, et al.
Publicado: (2005)

The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif
por: Ohlenschläger, Oliver, et al.
Publicado: (2012)

Stable maintenance of the Mre11-Rad50-Nbs1 complex is sufficient to restore the DNA double-strand break response in cells lacking RecQL4 helicase activity
por: Kim, Hyunsup, et al.
Publicado: (2021)

The intrinsically disordered amino-terminal region of human RecQL4: multiple DNA-binding domains confer annealing, strand exchange and G4 DNA binding
por: Keller, Heidi, et al.
Publicado: (2014)

Distinct prognosis of mRNA expression of the five RecQ DNA-helicase family members – RECQL, BLM, WRN, RECQL4, and RECQL5 – in patients with breast cancer
por: Zhu, Xuan, et al.
Publicado: (2018)

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair
por: Lu, Huiming, et al.
Publicado: (2017)

The human RecQ helicases BLM and RECQL4 cooperate to preserve genome stability
por: Singh, Dharmendra Kumar, et al.
Publicado: (2012)

Bacillus subtilis RecA and its accessory factors, RecF, RecO, RecR and RecX, are required for spore resistance to DNA double-strand break
por: Vlašić, Ignacija, et al.
Publicado: (2014)

Human RecQ Helicases in DNA Double-Strand Break Repair
por: Lu, Huiming, et al.
Publicado: (2021)

Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5
por: Newman, Joseph A., et al.
Publicado: (2017)

The cohesin-like RecN protein stimulates RecA-mediated recombinational repair of DNA double-strand breaks
por: Uranga, Lee A., et al.
Publicado: (2017)

RecG Directs DNA Synthesis during Double-Strand Break Repair
por: Azeroglu, Benura, et al.
Publicado: (2016)

REC drives recombination to repair double-strand breaks in animal mtDNA
por: Klucnika, Anna, et al.
Publicado: (2022)

TOPOVIBL-REC114 interaction regulates meiotic DNA double-strand breaks
por: Nore, Alexandre, et al.
Publicado: (2022)

DNA-PK(cs)-dependent phosphorylation of RECQL4 promotes NHEJ by stabilizing the NHEJ machinery at DNA double-strand breaks
por: Lu, Huiming, et al.
Publicado: (2022)

Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks
por: Poulsen, Maria, et al.
Publicado: (2012)

ATPase Activity of Bacillus subtilis RecA Affects the Dynamic Formation of RecA Filaments at DNA Double Strand Breaks
por: Hernández-Tamayo, Rogelio, et al.
Publicado: (2022)

RecG controls DNA amplification at double‐strand breaks and arrested replication forks
por: Azeroglu, Benura, et al.
Publicado: (2017)

XPD localizes in mitochondria and protects the mitochondrial genome from oxidative DNA damage
por: Liu, Jing, et al.
Publicado: (2015)

Arsenite Binds to the RING Finger Domains of RNF20-RNF40 Histone E3 Ubiquitin Ligase and Inhibits DNA Double-Strand Break Repair
por: Zhang, Fan, et al.
Publicado: (2014)

Opposing roles of RNF8/RNF168 and deubiquitinating enzymes in ubiquitination-dependent DNA double-strand break response signaling and DNA-repair pathway choice
por: Nakada, Shinichiro
Publicado: (2016)

Regulation of 53BP1 Protein Stability by RNF8 and RNF168 Is Important for Efficient DNA Double-Strand Break Repair
por: Hu, Yiheng, et al.
Publicado: (2014)

Dynamic formation of RecA filaments at DNA double strand break repair centers in live cells
por: Kidane, Dawit, et al.
Publicado: (2005)

Direct observation of end resection by RecBCD during double-stranded DNA break repair in vivo
por: Wiktor, Jakub, et al.
Publicado: (2018)

RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner
por: Kuo, Ching-Ying, et al.
Publicado: (2016)

RNF20-SNF2H Pathway of Chromatin Relaxation in DNA Double-Strand Break Repair
por: Kato, Akihiro, et al.
Publicado: (2015)

A Major Role of the RecFOR Pathway in DNA Double-Strand-Break Repair through ESDSA in Deinococcus radiodurans
por: Bentchikou, Esma, et al.
Publicado: (2010)

RecF protein targeting to postreplication (daughter strand) gaps I: DNA binding by RecF and RecFR
por: Henry, Camille, et al.
Publicado: (2023)

The process of displacing the single-stranded DNA-binding protein from single-stranded DNA by RecO and RecR proteins
por: Inoue, Jin, et al.
Publicado: (2008)

Correction to ‘RecF protein targeting to postreplication (daughter strand) gaps I: DNA binding by RecF and RecFR’
Publicado: (2023)

PcrA Dissociates RecA Filaments and the SsbA and RecO Mediators Counterbalance Such Activity
por: Carrasco, Begoña, et al.
Publicado: (2022)

RecBCD coordinates repair of two ends at a DNA double-strand break, preventing aberrant chromosome amplification
por: White, Martin A, et al.
Publicado: (2018)

Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with MEI4
por: Kumar, Rajeev, et al.
Publicado: (2018)

Characterization of the REC114‐MEI4‐IHO1 complex regulating meiotic DNA double‐strand break formation
por: Laroussi, Hamida, et al.
Publicado: (2023)

Ataxin‐3 consolidates the MDC1‐dependent DNA double‐strand break response by counteracting the SUMO‐targeted ubiquitin ligase RNF4
por: Pfeiffer, Annika, et al.
Publicado: (2017)

DNA replication arrest leads to enhanced homologous recombination and cell death in meristems of rice OsRecQl4 mutants
por: Kwon, Yong-Ik, et al.
Publicado: (2013)

A dual role for mycobacterial RecO in RecA-dependent homologous recombination and RecA-independent single-strand annealing
por: Gupta, Richa, et al.
Publicado: (2013)

Dynamics of RecA filaments on single-stranded DNA
por: van Loenhout, Marijn T. J., et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_03vb0pu6qo0tj6klv3ipm5sslo