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Granzyme B mediates impaired healing of pressure injuries in aged skin

Pressure injuries (PIs), also known as bedsores or pressure ulcers, are a major cause of death and morbidity in the elderly. The serine protease, Granzyme B (GzmB), contributes to skin aging and impaired wound healing. Aging is a major risk factor for PIs; thus, the role of GzmB in PI pathogenesis w...

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Detalles Bibliográficos
Autores principales: Turner, Christopher T., Bolsoni, Juliana, Zeglinski, Matthew R., Zhao, Hongyan, Ponomarev, Tatjana, Richardson, Katlyn, Hiroyasu, Sho, Schmid, Erin, Papp, Anthony, Granville, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935969/
https://www.ncbi.nlm.nih.gov/pubmed/33674592
http://dx.doi.org/10.1038/s41514-021-00059-6