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Granzyme B mediates impaired healing of pressure injuries in aged skin
Pressure injuries (PIs), also known as bedsores or pressure ulcers, are a major cause of death and morbidity in the elderly. The serine protease, Granzyme B (GzmB), contributes to skin aging and impaired wound healing. Aging is a major risk factor for PIs; thus, the role of GzmB in PI pathogenesis w...
Autores principales: | Turner, Christopher T., Bolsoni, Juliana, Zeglinski, Matthew R., Zhao, Hongyan, Ponomarev, Tatjana, Richardson, Katlyn, Hiroyasu, Sho, Schmid, Erin, Papp, Anthony, Granville, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935969/ https://www.ncbi.nlm.nih.gov/pubmed/33674592 http://dx.doi.org/10.1038/s41514-021-00059-6 |
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