Conditionally immortalised leukaemia initiating cells co-expressing Hoxa9/Meis1 demonstrate microenvironmental adaptation properties ex vivo while maintaining myelomonocytic memory

Regulation of haematopoietic stem cell fate through conditional gene expression could improve understanding of healthy haematopoietic and leukaemia initiating cell (LIC) biology. We established conditionally immortalised myeloid progenitor cell lines co-expressing constitutive Hoxa9.EGFP and inducib...

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Detalles Bibliográficos
Autores principales: Stahlhut, Maike, Ha, Teng Cheong, Takmakova, Ekaterina, Morgan, Michael A., Schwarzer, Adrian, Schaudien, Dirk, Eder, Matthias, Schambach, Axel, Kustikova, Olga S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935976/
https://www.ncbi.nlm.nih.gov/pubmed/33674652
http://dx.doi.org/10.1038/s41598-021-84468-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7935976/
https://www.ncbi.nlm.nih.gov/pubmed/33674652
http://dx.doi.org/10.1038/s41598-021-84468-3

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