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Association of Pathogenic Missense and Nonsense Mutations in Mitochondrial COII Gene with Familial Adenomatous Polyposis (FAP)

Nuclear genetic mutations have been extensively investigated in solid tumors. However, the role of the mitochondrial genome remains uncertain. Since the metabolism of solid tumors is associated with aerobic glycolysis and high lactate production, tumors may have mitochondrial dysfunctions. Familial...

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Detalles Bibliográficos
Autores principales: Shaker Ardakani, Zahra, Heidari, Mohammad Mehdi, Khatami, Mehri, Bitaraf Sani, Morteza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936074/
https://www.ncbi.nlm.nih.gov/pubmed/33688483
http://dx.doi.org/10.22088/IJMCM.BUMS.9.4.255