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Label‐free proteomic dissection on dptP‐deletion mutant uncovers dptP involvement in strain growth and daptomycin tolerance of Streptomyces roseosporus

Daptomycin (DAP) is a novel microbial lipopeptide antibiotic synthesized by the DAP biosynthetic gene cluster dpt of Streptomyces roseosporus (S. roseosporus). DptP gene locates upstream of dpt and confers DAP resistance to Streptomyces ambofaciens (S. ambofaciens). So far, the biological functions...

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Detalles Bibliográficos
Autores principales: Zhang, Dan, Wang, Xixi, Ye, Yang, He, Yu, He, Fuqiang, Tian, Yongqiang, Luo, Yunzi, Liang, Shufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936300/
https://www.ncbi.nlm.nih.gov/pubmed/33369164
http://dx.doi.org/10.1111/1751-7915.13736