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T cells selectively filter oscillatory signals on the minutes timescale

T cells experience complex temporal patterns of stimulus via receptor–ligand-binding interactions with surrounding cells. From these temporal patterns, T cells are able to pick out antigenic signals while establishing self-tolerance. Although features such as duration of antigen binding have been ex...

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Detalles Bibliográficos
Autores principales: O’Donoghue, Geoff P., Bugaj, Lukasz J., Anderson, Warren, Daniels, Kyle G., Rawlings, David J., Lim, Wendell A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936380/
https://www.ncbi.nlm.nih.gov/pubmed/33627405
http://dx.doi.org/10.1073/pnas.2019285118