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T cells selectively filter oscillatory signals on the minutes timescale
T cells experience complex temporal patterns of stimulus via receptor–ligand-binding interactions with surrounding cells. From these temporal patterns, T cells are able to pick out antigenic signals while establishing self-tolerance. Although features such as duration of antigen binding have been ex...
Autores principales: | O’Donoghue, Geoff P., Bugaj, Lukasz J., Anderson, Warren, Daniels, Kyle G., Rawlings, David J., Lim, Wendell A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936380/ https://www.ncbi.nlm.nih.gov/pubmed/33627405 http://dx.doi.org/10.1073/pnas.2019285118 |
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