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The CAD risk locus 9p21 increases the risk of vascular calcification in an iPSC-derived VSMC model
BACKGROUND: Coronary artery disease (CAD) is the leading cause of death worldwide. Chromosome locus 9p21 was the first to be associated with increased risk of CAD and coronary artery calcification (CAC). Vascular calcification increases the risk for CAD. Vascular smooth muscle cells (VSMCs) are one...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936418/ https://www.ncbi.nlm.nih.gov/pubmed/33676559 http://dx.doi.org/10.1186/s13287-021-02229-5 |