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Effect of fibronectin, FGF-2, and BMP4 in the stemness maintenance of BMSCs and the metabolic and proteomic cues involved

BACKGROUND: Growing evidence suggests that the pluripotent state of mesenchymal stem cells (MSCs) relies on specific local microenvironmental cues such as adhesion molecules and growth factors. Fibronectin (FN), fibroblast growth factor 2 (FGF2), and bone morphogenetic protein 4 (BMP4) are the key p...

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Detalles Bibliográficos
Autores principales: Chen, Lingling, Carlton, Morgan, Chen, Xiaodan, Kaur, Navdeep, Ryan, Hollie, Parker, Tony J, Lin, Zhengmei, Xiao, Yin, Zhou, Yinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936451/
https://www.ncbi.nlm.nih.gov/pubmed/33676544
http://dx.doi.org/10.1186/s13287-021-02227-7