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The influence of IFITM3 polymorphisms on susceptibility to SARS-CoV-2 infection and severity of COVID-19

BACKGROUND AND AIMS: The interferon-induced transmembrane protein 3 (IFITM3) plays an important role in the adaptive and innate immune response by inhibiting viral membrane hemifusion between the host and viral cell cytoplasm. Single nucleotide polymorphisms (SNPs) in the gene IFITM3 have been assoc...

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Detalles Bibliográficos
Autores principales: Schönfelder, Kristina, Breuckmann, Katharina, Elsner, Carina, Dittmer, Ulf, Fistera, David, Herbstreit, Frank, Risse, Joachim, Schmidt, Karsten, Sutharsan, Sivagurunathan, Taube, Christian, Jöckel, Karl-Heinz, Siffert, Winfried, Kribben, Andreas, Möhlendick, Birte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936555/
https://www.ncbi.nlm.nih.gov/pubmed/33711707
http://dx.doi.org/10.1016/j.cyto.2021.155492