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Laparoscopic surgery during the COVID-19 pandemic: detection of SARS-COV-2 in abdominal tissues, fluids, and surgical smoke

BACKGROUND: There are still concerns over the safety of laparoscopic surgery in coronavirus disease 2019 (COVID-19) patients due to the potential risk of viral transmission through surgical smoke/laparoscopic pneumoperitoneum. METHODS: We performed a systematic review of currently available literatu...

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Autores principales: Cheruiyot, Isaac, Sehmi, Prabjot, Ngure, Brian, Misiani, Musa, Karau, Paul, Olabu, Beda, Henry, Brandon Michael, Lippi, Giuseppe, Cirocchi, Roberto, Ogeng’o, Julius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936592/
https://www.ncbi.nlm.nih.gov/pubmed/33675407
http://dx.doi.org/10.1007/s00423-021-02142-8
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author Cheruiyot, Isaac
Sehmi, Prabjot
Ngure, Brian
Misiani, Musa
Karau, Paul
Olabu, Beda
Henry, Brandon Michael
Lippi, Giuseppe
Cirocchi, Roberto
Ogeng’o, Julius
author_facet Cheruiyot, Isaac
Sehmi, Prabjot
Ngure, Brian
Misiani, Musa
Karau, Paul
Olabu, Beda
Henry, Brandon Michael
Lippi, Giuseppe
Cirocchi, Roberto
Ogeng’o, Julius
author_sort Cheruiyot, Isaac
collection PubMed
description BACKGROUND: There are still concerns over the safety of laparoscopic surgery in coronavirus disease 2019 (COVID-19) patients due to the potential risk of viral transmission through surgical smoke/laparoscopic pneumoperitoneum. METHODS: We performed a systematic review of currently available literature to determine the presence of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) in abdominal tissues or fluids and in surgical smoke. RESULTS: A total of 19 studies (15 case reports and 4 case series) comprising 29 COVID-19 patients were included. The viral RNA was positively identified in 11 patients (37.9%). The samples that tested positive include the peritoneal fluid, bile, ascitic fluid, peritoneal dialysate, duodenal wall, and appendix. Similar samples, together with the omentum and abdominal subcutaneous fat, tested negative in the other patients. Only one study investigated SARS-COV-2 RNA in surgical smoke generated during laparoscopy, reporting negative findings. CONCLUSIONS: There are conflicting results regarding the presence of SARS-COV-2 in abdominal tissues and fluids. No currently available evidence supports the hypothesis that SARS-COV-2 can be aerosolized and transmitted through surgical smoke. Larger studies are urgently needed to corroborate these findings. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00423-021-02142-8.
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spelling pubmed-79365922021-03-08 Laparoscopic surgery during the COVID-19 pandemic: detection of SARS-COV-2 in abdominal tissues, fluids, and surgical smoke Cheruiyot, Isaac Sehmi, Prabjot Ngure, Brian Misiani, Musa Karau, Paul Olabu, Beda Henry, Brandon Michael Lippi, Giuseppe Cirocchi, Roberto Ogeng’o, Julius Langenbecks Arch Surg Systematic Reviews and Meta-analyses BACKGROUND: There are still concerns over the safety of laparoscopic surgery in coronavirus disease 2019 (COVID-19) patients due to the potential risk of viral transmission through surgical smoke/laparoscopic pneumoperitoneum. METHODS: We performed a systematic review of currently available literature to determine the presence of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) in abdominal tissues or fluids and in surgical smoke. RESULTS: A total of 19 studies (15 case reports and 4 case series) comprising 29 COVID-19 patients were included. The viral RNA was positively identified in 11 patients (37.9%). The samples that tested positive include the peritoneal fluid, bile, ascitic fluid, peritoneal dialysate, duodenal wall, and appendix. Similar samples, together with the omentum and abdominal subcutaneous fat, tested negative in the other patients. Only one study investigated SARS-COV-2 RNA in surgical smoke generated during laparoscopy, reporting negative findings. CONCLUSIONS: There are conflicting results regarding the presence of SARS-COV-2 in abdominal tissues and fluids. No currently available evidence supports the hypothesis that SARS-COV-2 can be aerosolized and transmitted through surgical smoke. Larger studies are urgently needed to corroborate these findings. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00423-021-02142-8. Springer Berlin Heidelberg 2021-03-06 2021 /pmc/articles/PMC7936592/ /pubmed/33675407 http://dx.doi.org/10.1007/s00423-021-02142-8 Text en © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Systematic Reviews and Meta-analyses
Cheruiyot, Isaac
Sehmi, Prabjot
Ngure, Brian
Misiani, Musa
Karau, Paul
Olabu, Beda
Henry, Brandon Michael
Lippi, Giuseppe
Cirocchi, Roberto
Ogeng’o, Julius
Laparoscopic surgery during the COVID-19 pandemic: detection of SARS-COV-2 in abdominal tissues, fluids, and surgical smoke
title Laparoscopic surgery during the COVID-19 pandemic: detection of SARS-COV-2 in abdominal tissues, fluids, and surgical smoke
title_full Laparoscopic surgery during the COVID-19 pandemic: detection of SARS-COV-2 in abdominal tissues, fluids, and surgical smoke
title_fullStr Laparoscopic surgery during the COVID-19 pandemic: detection of SARS-COV-2 in abdominal tissues, fluids, and surgical smoke
title_full_unstemmed Laparoscopic surgery during the COVID-19 pandemic: detection of SARS-COV-2 in abdominal tissues, fluids, and surgical smoke
title_short Laparoscopic surgery during the COVID-19 pandemic: detection of SARS-COV-2 in abdominal tissues, fluids, and surgical smoke
title_sort laparoscopic surgery during the covid-19 pandemic: detection of sars-cov-2 in abdominal tissues, fluids, and surgical smoke
topic Systematic Reviews and Meta-analyses
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936592/
https://www.ncbi.nlm.nih.gov/pubmed/33675407
http://dx.doi.org/10.1007/s00423-021-02142-8
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