Short loop functional commonality identified in leukaemia proteome highlights crucial protein sub-networks

Direct drug targeting of mutated proteins in cancer is not always possible and efficacy can be nullified by compensating protein–protein interactions (PPIs). Here, we establish an in silico pipeline to identify specific PPI sub-networks containing mutated proteins as potential targets, which we appl...

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Detalles Bibliográficos
Autores principales: Chung, Sun Sook, Ng, Joseph C F, Laddach, Anna, Thomas, N Shaun B, Fraternali, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Standard Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936661/
https://www.ncbi.nlm.nih.gov/pubmed/33709075
http://dx.doi.org/10.1093/nargab/lqab010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936661/
https://www.ncbi.nlm.nih.gov/pubmed/33709075
http://dx.doi.org/10.1093/nargab/lqab010

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