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Short loop functional commonality identified in leukaemia proteome highlights crucial protein sub-networks
Direct drug targeting of mutated proteins in cancer is not always possible and efficacy can be nullified by compensating protein–protein interactions (PPIs). Here, we establish an in silico pipeline to identify specific PPI sub-networks containing mutated proteins as potential targets, which we appl...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936661/ https://www.ncbi.nlm.nih.gov/pubmed/33709075 http://dx.doi.org/10.1093/nargab/lqab010 |