Long-term safety and efficacy of givinostat in polycythemia vera: 4-year mean follow up of three phase 1/2 studies and a compassionate use program

Polycythemia vera (PV) is a BCR-ABL1-negative myeloproliferative neoplasm (MPN) characterized by excessive proliferation of erythroid, myeloid, and megakaryocytic components in the bone marrow, mainly due to a Janus kinase 2 gene mutation (JAK2(V617F)). Givinostat, a histone-deacetylase inhibitor th...

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Detalles Bibliográficos
Autores principales: Rambaldi, Alessandro, Iurlo, Alessandra, Vannucchi, Alessandro M., Martino, Bruno, Guarini, Attilio, Ruggeri, Marco, von Bubnoff, Nikolas, De Muro, Marianna, McMullin, Mary Frances, Luciani, Stefania, Martinelli, Vincenzo, Nogai, Axel, Rosti, Vittorio, Ricco, Alessandra, Bettica, Paolo, Manzoni, Sara, Di Tollo, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936975/
https://www.ncbi.nlm.nih.gov/pubmed/33677466
http://dx.doi.org/10.1038/s41408-021-00445-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7936975/
https://www.ncbi.nlm.nih.gov/pubmed/33677466
http://dx.doi.org/10.1038/s41408-021-00445-z

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