Sustained-release diclofenac conjugated to hyaluronate (diclofenac etalhyaluronate) for knee osteoarthritis: a randomized phase 2 study

OBJECTIVE: To evaluate the efficacy and safety of diclofenac etalhyaluronate (DF-HA) (ONO-5704/SI-613), a novel DF-conjugated hyaluronate, in patients with knee OA in Japan. METHODS: In this randomized, double-blind, placebo-controlled phase 2 study, patients were randomly assigned (1:1) to receive...

Descripción completa

Detalles Bibliográficos
Autores principales: Nishida, Yoshihiro, Kano, Kazuyuki, Nobuoka, Yuji, Seo, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937021/
https://www.ncbi.nlm.nih.gov/pubmed/33006602
http://dx.doi.org/10.1093/rheumatology/keaa605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937021/
https://www.ncbi.nlm.nih.gov/pubmed/33006602
http://dx.doi.org/10.1093/rheumatology/keaa605

Ejemplares similares