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Sustained-release diclofenac conjugated to hyaluronate (diclofenac etalhyaluronate) for knee osteoarthritis: a randomized phase 2 study

OBJECTIVE: To evaluate the efficacy and safety of diclofenac etalhyaluronate (DF-HA) (ONO-5704/SI-613), a novel DF-conjugated hyaluronate, in patients with knee OA in Japan. METHODS: In this randomized, double-blind, placebo-controlled phase 2 study, patients were randomly assigned (1:1) to receive...

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Detalles Bibliográficos
Autores principales:	Nishida, Yoshihiro, Kano, Kazuyuki, Nobuoka, Yuji, Seo, Takayuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Clinical Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937021/ https://www.ncbi.nlm.nih.gov/pubmed/33006602 http://dx.doi.org/10.1093/rheumatology/keaa605

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