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Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration

OBJECTIVE: To identify OA subtypes based on cartilage transcriptomic data in cartilage tissue and characterize their underlying pathophysiological processes and/or clinically relevant characteristics. METHODS: This study includes n = 66 primary OA patients (41 knees and 25 hips), who underwent a joi...

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Detalles Bibliográficos
Autores principales: Coutinho de Almeida, Rodrigo, Mahfouz, Ahmed, Mei, Hailiang, Houtman, Evelyn, den Hollander, Wouter, Soul, Jamie, Suchiman, Eka, Lakenberg, Nico, Meessen, Jennifer, Huetink, Kasper, Nelissen, Rob G H H, Ramos, Yolande F M, Reinders, Marcel, Meulenbelt, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937023/
https://www.ncbi.nlm.nih.gov/pubmed/32885253
http://dx.doi.org/10.1093/rheumatology/keaa391