Hippocampal neurons isolated from rats subjected to the valproic acid model mimic in vivo synaptic pattern: evidence of neuronal priming during early development in autism spectrum disorders

BACKGROUND: Autism spectrum disorders (ASD) are synaptopathies characterized by area-specific synaptic alterations and neuroinflammation. Structural and adhesive features of hippocampal synapses have been described in the valproic acid (VPA) model. However, neuronal and microglial contribution to hi...

Descripción completa

Detalles Bibliográficos
Autores principales: Traetta, Marianela Evelyn, Codagnone, Martín Gabriel, Uccelli, Nonthué Alejandra, Ramos, Alberto Javier, Zárate, Sandra, Reinés, Analía
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937248/
https://www.ncbi.nlm.nih.gov/pubmed/33676530
http://dx.doi.org/10.1186/s13229-021-00428-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937248/
https://www.ncbi.nlm.nih.gov/pubmed/33676530
http://dx.doi.org/10.1186/s13229-021-00428-8

Ejemplares similares