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Prediction of activity and selectivity profiles of human Carbonic Anhydrase inhibitors using machine learning classification models
The development of selective inhibitors of the clinically relevant human Carbonic Anhydrase (hCA) isoforms IX and XII has become a major topic in drug research, due to their deregulation in several types of cancer. Indeed, the selective inhibition of these two isoforms, especially with respect to th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937250/ https://www.ncbi.nlm.nih.gov/pubmed/33676550 http://dx.doi.org/10.1186/s13321-021-00499-y |