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Blockage of NLRP3 inflammasome activation ameliorates acute inflammatory injury and long-term cognitive impairment induced by necrotizing enterocolitis in mice

BACKGROUND: Necrotizing enterocolitis (NEC) is an inflammatory gastrointestinal disease in premature neonates with high mortality and morbidity, while the underlining mechanism of intestinal injury and profound neurological dysfunction remains unclear. Here, we aimed to investigate the involvement o...

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Detalles Bibliográficos
Autores principales: Zhu, Fangxinxing, Wang, Lingyu, Gong, Zizhen, Wang, Yanyan, Gao, Yanhong, Cai, Wei, Wu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937302/
https://www.ncbi.nlm.nih.gov/pubmed/33676524
http://dx.doi.org/10.1186/s12974-021-02111-4