Comparative engraftment and clonality of macaque HSPCs expanded on human umbilical vein endothelial cells versus non-expanded cells

Ex vivo hematopoietic stem and progenitor cell (HSPC) expansion platforms are under active development, designed to increase HSPC numbers and thus engraftment ability of allogeneic cord blood grafts or autologous HSPCs for gene therapies. Murine and in vitro models have not correlated well with clin...

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Detalles Bibliográficos
Autores principales: Srivastava, Sandeep K., Truitt, Lauren L., Wu, Chuanfeng, Glaser, Adam, Nolan, Daniel J., Ginsberg, Michael, Espinoza, Diego A., Koelle, Samson, Yabe, Idalia M., Yu, Kyung-Rok, Hong, Sogun, Sellers, Stephanie, Krouse, Allen, Bonifacino, Aylin, Metzger, Mark, Dagur, Pradeep K., Donahue, Robert E., Dunbar, Cynthia E., Panch, Sandhya R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937567/
https://www.ncbi.nlm.nih.gov/pubmed/33738325
http://dx.doi.org/10.1016/j.omtm.2021.02.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937567/
https://www.ncbi.nlm.nih.gov/pubmed/33738325
http://dx.doi.org/10.1016/j.omtm.2021.02.009

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