CTCF Mediates Replicative Senescence Through POLD1

POLD1, the catalytic subunit of DNA polymerase δ, plays a critical role in DNA synthesis and DNA repair processes. Moreover, POLD1 is downregulated in replicative senescence to mediate aging. In any case, the components of age-related downregulation of POLD1 expression have not been fully explained....

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, Yuli, Song, Qiao, Gao, Shichao, Zhang, Xiaomin, Wang, Yaqi, Liu, Jing, Fu, Jingxuan, Cao, Min, Wang, Peichang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937641/
https://www.ncbi.nlm.nih.gov/pubmed/33692996
http://dx.doi.org/10.3389/fcell.2021.618586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937641/
https://www.ncbi.nlm.nih.gov/pubmed/33692996
http://dx.doi.org/10.3389/fcell.2021.618586

Ejemplares similares