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Characterization of the CDAA Diet-Induced Non-alcoholic Steatohepatitis Model: Sex-Specific Differences in Inflammation, Fibrosis, and Cholesterol Metabolism in Middle-Aged Mice

BACKGROUND: The prevalence of non-alcoholic steatohepatitis (NASH) rapidly increases with associated metabolic disorders such as dyslipidemia; therefore, NASH is now considered an independent risk factor of cardiovascular diseases. NASH displays sex-linked epidemiological, phenotypical, and molecula...

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Detalles Bibliográficos
Autores principales: Kucsera, Dániel, Tóth, Viktória E., Gergő, Dorottya, Vörös, Imre, Onódi, Zsófia, Görbe, Anikó, Ferdinandy, Péter, Varga, Zoltán V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937716/
https://www.ncbi.nlm.nih.gov/pubmed/33692700
http://dx.doi.org/10.3389/fphys.2021.609465