Cargando…

Establishment and Characterization of an Irinotecan-Resistant Human Colon Cancer Cell Line

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. Irinotecan is widely used as a chemotherapeutic drug to treat CRC. However, the mechanisms of acquired resistance to irinotecan in CRC remain inconclusive. In the present study, we established a novel irinotecan-resistant...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Zhuo-Xun, Yang, Yuqi, Zeng, Leli, Patel, Harsh, Bo, Letao, Lin, Lusheng, Chen, Zhe-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937870/
https://www.ncbi.nlm.nih.gov/pubmed/33692943
http://dx.doi.org/10.3389/fonc.2020.624954