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Establishment and Characterization of an Irinotecan-Resistant Human Colon Cancer Cell Line
Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. Irinotecan is widely used as a chemotherapeutic drug to treat CRC. However, the mechanisms of acquired resistance to irinotecan in CRC remain inconclusive. In the present study, we established a novel irinotecan-resistant...
Autores principales: | Wu, Zhuo-Xun, Yang, Yuqi, Zeng, Leli, Patel, Harsh, Bo, Letao, Lin, Lusheng, Chen, Zhe-Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937870/ https://www.ncbi.nlm.nih.gov/pubmed/33692943 http://dx.doi.org/10.3389/fonc.2020.624954 |
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