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Hyperactive Behavior and Altered Brain Morphology in Adult Complement C3a Receptor Deficient Mice

The C3a receptor (C3aR) is a seven trans-membrane domain G-protein coupled receptor with a range of immune modulatory functions. C3aR is activated by the third complement component (C3) activation derived peptide C3a and a neuropeptide TLQP-21. In the central nervous system (CNS), C3aR is expressed...

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Detalles Bibliográficos
Autores principales: Pozo-Rodrigálvarez, Andrea, Ollaranta, Roosa, Skoog, Jenny, Pekny, Milos, Pekna, Marcela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937871/
https://www.ncbi.nlm.nih.gov/pubmed/33692783
http://dx.doi.org/10.3389/fimmu.2021.604812