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Methylprednisolone Treatment in Brain Death-Induced Lung Inflammation–A Dose Comparative Study in Rats

Background: The process of brain death (BD) leads to a pro-inflammatory state of the donor lung, which deteriorates its quality. In an attempt to preserve lung quality, methylprednisolone is widely recommended in donor lung management. However, clinical treatment doses vary and the dose-effect relat...

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Detalles Bibliográficos
Autores principales: Van Zanden, Judith E., ’T Hart, Nils A., Ottens, Petra J., Liu, Bo, Rebolledo, Rolando A., Erasmus, Michiel E., Leuvenink, Henri G. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937885/
https://www.ncbi.nlm.nih.gov/pubmed/33692687
http://dx.doi.org/10.3389/fphar.2021.587003