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Modeling Maturity Onset Diabetes of the Young in Pluripotent Stem Cells: Challenges and Achievements

Maturity onset diabetes of the young (MODY), is a group of monogenic diabetes disorders. Rodent models for MODY do not fully recapitulate the human phenotypes, calling for models generated in human cells. Human pluripotent stem cells (hPSCs), capable of differentiation towards pancreatic cells, poss...

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Detalles Bibliográficos
Autores principales: Braverman-Gross, Carmel, Benvenisty, Nissim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937923/
https://www.ncbi.nlm.nih.gov/pubmed/33692757
http://dx.doi.org/10.3389/fendo.2021.622940