Chenodeoxycholic Acid Modulates Bile Acid Synthesis Independent of Fibroblast Growth Factor 19 in Primary Human Hepatocytes

Bile acids (BAs) are detergents essential for intestinal absorption of lipids. Disruption of BA homeostasis can lead to severe liver damage. BA metabolism is therefore under strict regulation by sophisticated feedback mechanisms. The hormone-like protein Fibroblast growth factor 19 (FGF19) is essent...

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Detalles Bibliográficos
Autores principales: Johansson, Helene, Søndergaard, Jonas Nørskov, Jorns, Carl, Kutter, Claudia, Ellis, Ewa C. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937932/
https://www.ncbi.nlm.nih.gov/pubmed/33692750
http://dx.doi.org/10.3389/fendo.2020.554922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937932/
https://www.ncbi.nlm.nih.gov/pubmed/33692750
http://dx.doi.org/10.3389/fendo.2020.554922

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